Procter & Gamble's product label warns it is not indicated for children under two. But Rubin said some parents may still choose to use it for a sick child, usually by rubbing the salve on the feet or chest.
"The ingredients in Vicks can be irritants, causing the body to produce more mucus to protect the airway," said Rubin.
"Infants and young children have airways that are much narrower than those of adults, so any increase in mucus or inflammation can narrow them more severely."
In the January issue of the journal Chest, Rubin and his colleagues tested the effects of Vicks Vapo Rub on the respiratory system of ferrets, laboratory animals with a similar airway anatomy and cellular makeup as humans.
Test tube results showed Vicks VapoRub exposure increased mucus secretion in the animals' airways, whether the tracheas were normal or inflamed to simulate a person with a chest infection.
"Some of the ingredients in Vicks, notably the menthol, trick the brain into thinking that it is easier to breathe by triggering a cold sensation, which is processed as indicating more airflow," he said. "Vicks may make you feel better but it can't help you breathe better."
"This may be of little physiologic consequence in older children and adults, but in infants and small children this potentially can lead to respiratory distress," the study's authors concluded.
Rubin said he recommends never putting Vicks in, or under, the nose of anyone, regardless of their age.
Parents should also follow the directions and not use Vicks or similar generic products on children under two, he advised.
On Dec. 18, 2008, Health Canada said children under six year old shouldn't be treated with cough and cold medication, citing reports of misuse, overdose and rare side-effects.
The best treatments for congestion are saline (salt water), gentle suction with a rubber bulb, warm drinks or chicken soup, and time, the researchers said, noting if a child is struggling to breathe, then it's a medical emergency.
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